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CASE REPORT
Year : 2020  |  Volume : 26  |  Issue : 4  |  Page : 289-292

Otological manifestations of Langerhans cell histiocytosis in a child - An enigma that persists!


1 Department of Otorhinolaryngology, University Kebangsaan Malaysia Medical Center; Department of Otorhinolaryngology, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia
2 Department of Otorhinolaryngology; Center for Ear, Hearing and Speech (Pusat HEARS), University Kebangsaan Malaysia Medical Center, Kuala Lumpur, Malaysia
3 Department of Otorhinolaryngology, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia
4 Department of Pathology, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia

Correspondence Address:
Dr. Chow Xiao Hong
Department of Otorhinolaryngology, University Kebangsaan Malaysia Medical Center, Kuala Lumpur
Malaysia
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/indianjotol.INDIANJOTOL_69_20

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Langerhans cell histiocytosis (LCH) is a rare nonmalignant entity commonly seen in the pediatric population which encompasses a variety of clinical presentations. Otological involvement in LCH is uncommon which can be manifested as symptoms similar to otomastoiditis or malignancy, thus diagnosis is often delayed. Herein, we report a 1-year 7-month-old boy presented with unresolving left otorrhea complicated with left postauricular swelling. Otoscopic examination revealed granulation tissue in the left external auditory canal. Initial diagnosis of left otomastoiditis was made until high-resolution contrast-enhanced computed tomography of the temporal bone showed soft-tissue masses occupying bilateral mastoids with bony destruction. Histopathological examination with immunohistochemical staining expressed CD1a cytoplasmic immunoreactivity. The diagnosis of LCH was made. This report serves to highlight such a rare clinical entity which often masquerades as other otological diseases and hence becomes a diagnostic challenge in the pediatric population.


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