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Year : 2014  |  Volume : 20  |  Issue : 4  |  Page : 208-210

Diagonal earlobe crease and coronary artery disease in Iranian population: A marker for evaluating coronary risk

1 Department of Cardiology, Tehran University of Medical Sciences, Tehran, Iran
2 Department of Internal Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
3 Department of Internal Medicine, Tehran University of Medical Sciences, Tehran, Iran
4 Young Researchers Club, Islamic Azad University, Babol Branch, Babol, Iran

Correspondence Address:
Mahmood Montazeri
Young Researchers Club, Islamic Azad University, Babol Branch, Babol
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0971-7749.146941

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Background: The diagonal earlobe crease (DELC) has been proposed to be a marker of coronary artery disease (CAD), but this association remains controversial. The aim of the present study was to evaluate the frequency of DELC in patients with CAD. Materials and Methods: One hundred patients with angiographically documented CAD from Tehran Heart Center were evaluated for the presence or absence of ELC. The ELC was said to be present if a patient had a deep diagonal crease extending obliquely from the outer ear canal toward the border of the earlobe without discontinuity covering at least two-thirds of the earlobe length. Results: The prevalence of ELC was 62% (95% confidence interval 59.7-64.6). The frequency of smoking and hyperlipidemia was significantly higher in patients with DELC (P = 0.024 and P = 0.001, respectively). However, frequency of hypertension and diabetes were not significantly different between the two groups. Conclusion: The frequency of DELC in patients with CAD was high in our study. The data suggest that the ELC sign may be a useful marker for the presence of CAD in patients.

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