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Year : 2012  |  Volume : 18  |  Issue : 4  |  Page : 174-178

Noise-induced hearing loss: Recent advances in pharmacological management


Department ENT, Institute of Aerospace Medicine, Bangalore, Karnataka, India

Correspondence Address:
Renu Rajguru
Institute of Aerospace Medicine, Vimanpura, Near Hal Airport, Bangalore, Karnataka - 560 017
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0971-7749.104792

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Modern day high-performance machines, weapons, aircrafts and locomotives are more powerful, more efficient, and unfortunately, frequently produce high noise levels resulting in Noise-induced Hearing Loss (NIHL). Mechanical hearing protection is essential and effective; however, inherent limitations allow a significant percentage of permanent hearing loss to occur despite protection. Hence, a pharmacological preventative or rescue agent for NIHL forms an important element of a comprehensive approach to maintaining inner ear functional integrity in individuals exposed to noise. The ideal pharmacologic agent would specifically address known mechanisms of acoustic injury, be orally administered, be exceptionally safe, be effective and affordable. Though currently such a pharmacological agent is not available, but the ongoing research is promising. In this article, we discuss various pharmacological agents for prevention and management of NIHL.


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